Research Articles
E2F5 in Cancer: The Cellular Double Agent That Decides Fate
Explore the dual role of E2F5 transcription factor in cancer development - acting as both gatekeeper and destroyer in tumor cell cycle regulation.
New Cancer Inhibitor Candidate: Quercetin from Ciplukan Revealed Through Bioinformatics Analysis
Discover how bioinformatics reveals quercetin from ciplukan (Physalis angulata) as a promising natural cancer inhibitor through molecular docking and computational analysis.
The Epigenetic Guardian: How a Cellular Machine Fights Esophageal Cancer
Discover how epigenetic regulator KDM4D restricts tumorigenesis via modulating SYVN1/HMGB1 ubiquitination axis in esophageal squamous cell carcinoma.
Beyond One-Size-Fits-All: The Quest for Universal Biomarkers in Cancer Immunotherapy
Exploring the search for reliable biomarkers to predict response to CTLA-4 and PD-1 blockade immunotherapy across different cancer types.
Redox Switches: How Nitric Oxide Remodels a Cancer Chaperone
Exploring how nitric oxide remodels the TRAP1 cancer chaperone through S-nitrosylation and population-shift mechanisms
How a Cellular Chameleon Fuels Cancer's Drug Resistance
Discover how TRIP13 protein rewires cancer cell metabolism to promote stemness and chemotherapy resistance in colorectal cancer.
Beyond the Gene Sequence: How KRAS Mutation Dynamics Are Rewriting Cancer Treatment Rules
Explore how molecular dynamics simulations are revolutionizing our understanding of KRAS mutations in cancer, moving beyond traditional genomics to dynamic characterization.
ZNFX1: The Cell's Hidden Weapon in the Fight Against Cancer
Discover how ZNFX1, a master regulator protein, activates cancer cell self-destruction through pathogen mimicry and mitochondrial signaling pathways.
The Hidden Pattern: How DNA Co-Methylation Clusters Are Rewriting Cancer's Code
Discover how coordinated DNA methylation patterns are unveiling a new layer of genetic regulation that could transform cancer detection and treatment.
Rewriting Our Defenses: How Engineered T Cells Are Revolutionizing Cancer Treatment
Explore how genetically engineered T-cell therapy is transforming the fight against virus-related cancers through innovative immunotherapy approaches.